The term nucleolus , which can also be mentioned as nucleolus (with emphasis on AND ), comes from the Latin word nucleŏlus. The concept is used in the field of biology to allude to a organelle of the cells .
Organelles are functional and structural units of cells. In the case of nucleoli, they are inside the nucleus and allow synthesizing the ribonucleic acid (RNA ) of the ribosomes.
It is often said that the nucleolus is the area formed by RNA and proteins inside the nucleus . In this place the generation of the ribosomes , other organelles that contribute to the union of amino acids for protein production.
In the nucleolus, therefore, the different subunits that give rise to the appearance of the transcripts are transcribed, processed and assembled. ribosomes . Although the synthesis and conformation of ribosomes is their most important function, nucleoli also carry out other tasks: there are hundreds of proteins from these organelles that do not participate in the biogenesis of ribosomes.
It is important to mention, on the other hand, that the structure of the nucleolus is not delimited by a membrane . It is a dense or prominent area of the nucleus that is divided into several regions and is usually surrounded by heterochromatin.
The protein they associate and separate from the components of the nucleolus frequently. That is why the nucleolus is qualified as a dynamic element.
According to various studies, the virus they require the proteins that the nucleolus has to replicate. Therefore, when an infection occurs, the composition and morphology of the nucleolus are modified. The activity of the nucleolus, meanwhile, could also be related to the malignant proliferation of cells.